Global Markets

TRVI: Haduvio’s $15B Market Potential and TSMC’s Nalbuphine Supply Risks

724FinanceDr. Yaman Ege
TRVI: Haduvio’s $15B Market Potential and TSMC’s Nalbuphine Supply Risks

Trevi Therapeutics (TRVI) shares surged 9.85% after reporting strong clinical trial results for Haduvio, its chronic cough treatment candidate. The company is targeting a $14-15 billion addressable market for chronic cough, which is expected to grow at a 6% CAGR from $9 billion in 2024. TRVI plans to launch a Phase 2b trial for non-IPF ILD-related chronic cough in the second half of 2026. Hedge funds are increasing exposure ahead of potential approval.

TSMC’s supply chain risks in nalbuphine production, coupled with China-US semiconductor tensions, could disrupt TRVI’s timeline. The reliance on rare earth elements from the US threatens production continuity.
Dr. Yaman Ege

Financial Analyst: Dr. Yaman Ege

Semiconductor and Tech Supply Chain Director. Industrial futurist analyzing TSMC capacities, ASML machines, and the US-China rare earth war's impact on tech stocks.

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